Preimplantation Genetic procedure is essential for couples with repeated IVF failures, repeated abortions (habitual abortions) and aged couples, commonly done as PGT-A, for aged women to identify aneuploid embryos., with aberrant chromosomal numbers.
The identification of Hereditary diseases when family history is elicited is very essential to avoid continuation of similar diseases further- PGS or PGD.
Here few (minimum 4 cells) from the outer cells of the Blastocyst are aspirated using specific pipette , with the help of micromanipulator and inverted microscope , then the same are subjected for genetic testing – Next Gen Sequencing . If the cell seems to be normal then the embryo is declared as fit ones to transfer in to uterus.